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Novel Reagent Using Spectrophotometry

Sensitive detection of iron (II) sulfate with a novel reagent using spectrophotometry

In this study, a novel reagent was developed for sensitive detection of iron (II) sulfate, spectrophotometrically. A novel thio-anthraquinone derivative, 1-(Dodecylthio)anthracene-9,10-dione (3), was synthesized from the chemical reaction of 1-Chloroanthraquinone (1) and 1-Dodecanethiol (2) by an original reaction method and was used in the preparation of the novel reagent called Catal’s reagent.
  • A synthesized thio-anthraquinone analogue (3) was purified by column chromatography, and its chemical structure was characterized by spectroscopic methods such as Fourier-transform infrared spectroscopy (FT-IR), nuclear magnetic resonance (NMR) spectroscopy, mass spectrometry (MS), and ultraviolet (UV)-visible spectrophotometry.
  • The chemical and molecular structure of the developed thio-antraquinone derivative (3) was illuminated using computational methods with the GaussView5 and Gaussian09 programs. Various solvents including ethanol, methanol, and acetonitrile were examined in the preparation of the reagent. A concentration range from 0.2 mg mL-1 up to 10 mg mL-1 of iron (II) sulfate heptahydrate solution in distilled water was prepared. The absorption spectra of Catal’s reagent (0.816 mM) showed three peaks between 185 nm-700 nm of wavelength.
  • However, after the reaction with H2O2 and the 30 mM trisodium citrate dihydrate mixture in the presence of an iron sulfate (II) solution, a single peak was observed, producing a stable and reddish/brownish homogenous solution (λ max = 304 nm).
  • The following concentrations of iron (II) sulfate heptahydrate was examined using developed protocol and the reagent, and the concentrations were measured spectrophotometrically at 304 nm, 0.2-1 mg mL-1. Absorbances of reaction mixtures of iron (II) sulfate remained stable up to 48 h.
  • The results indicated that the novel Catal’s reagent can be used for sensitive spectrophotometric detection of iron (II) sulfate in aqueous solutions.
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gentaur

PeliKine tool set, additional reagents

M1980 1 unit
EUR 169.8

Alkphos Direct Labelling Reagents - EACH

RPN3680 EACH
EUR 915.3

Free Chlorine Reagents 0-5mg/L - EACH

WAT1028 EACH
EUR 49.95

Bradford(Coomassie) Protein Assay Plus Reagents

P7201-050 450ml
EUR 118

Bradford(Coomassie) Protein Assay Plus Reagents

P7201-100 950ml
EUR 130

iN-fect™ In vitro transfection reagents

15081 500 µL
EUR 127.27
Description: Transfection

Pre-Titrated Reagents for Human EGF ELISA

MBS590076-10Plates 10Plates
EUR 710

Pre-Titrated Reagents for Human EGF ELISA

MBS590076-5Plates 5Plates
EUR 520

Pre-Titrated Reagents for Human EGF ELISA

MBS590076-5x10Plates 5x10Plates
EUR 3270

Leeporter Assay Reagent- 1000 Test

MBS668917-1Kit 1Kit
EUR 770

Leeporter Assay Reagent- 1000 Test

MBS668917-5x1Kit 5x1Kit
EUR 3280

Liposomal and Non-Liposomal Transfection Reagents

abx298032-100g 100 µg Ask for price

Liposomal and Non-Liposomal Transfection Reagents

abx298032-20g 20 µg
EUR 875

Liposomal and Non-Liposomal Transfection Reagents

abx298032-50g 50 µg Ask for price

Pre-Titrated Reagents for Human IL-8 ELISA

MBS590074-10Plates 10Plates
EUR 710

Pre-Titrated Reagents for Human IL-8 ELISA

MBS590074-5Plates 5Plates
EUR 520

Pre-Titrated Reagents for Human IL-8 ELISA

MBS590074-5x10Plates 5x10Plates
EUR 3270

Pre-Titrated Reagents for Human MCP-1 ELISA

MBS590075-10Plates 10Plates
EUR 710

Pre-Titrated Reagents for Human MCP-1 ELISA

MBS590075-5Plates 5Plates
EUR 520

Pre-Titrated Reagents for Human MCP-1 ELISA

MBS590075-5x10Plates 5x10Plates
EUR 3270

Pre-Titrated Reagents for Human MCP-3 ELISA

MBS590077-10Plates 10Plates
EUR 710

Pre-Titrated Reagents for Human MCP-3 ELISA

MBS590077-5Plates 5Plates
EUR 520

Pre-Titrated Reagents for Human MCP-3 ELISA

MBS590077-5x10Plates 5x10Plates
EUR 3270

Pre-Titrated Reagents for Human IL-16 ELISA

MBS590080-10Plates 10Plates
EUR 710

Pre-Titrated Reagents for Human IL-16 ELISA

MBS590080-5Plates 5Plates
EUR 520

Pre-Titrated Reagents for Human IL-16 ELISA

MBS590080-5x10Plates 5x10Plates
EUR 3270

Pre-Titrated Reagents for Human IL-18 ELISA

MBS590083-10Plates 10Plates
EUR 710

Pre-Titrated Reagents for Human IL-18 ELISA

MBS590083-5Plates 5Plates
EUR 520

Pre-Titrated Reagents for Human IL-18 ELISA

MBS590083-5x10Plates 5x10Plates
EUR 3270

Pre-Titrated Reagents for Human GM-CSF ELISA

MBS590079-10Plates 10Plates
EUR 710

Pre-Titrated Reagents for Human GM-CSF ELISA

MBS590079-5Plates 5Plates
EUR 520

Pre-Titrated Reagents for Human GM-CSF ELISA

MBS590079-5x10Plates 5x10Plates
EUR 3270

Pre-Titrated Reagents for Human TNF-alpha ELISA

MBS590078-10Plates 10Plates
EUR 710

Pre-Titrated Reagents for Human TNF-alpha ELISA

MBS590078-5Plates 5Plates
EUR 520

Pre-Titrated Reagents for Human TNF-alpha ELISA

MBS590078-5x10Plates 5x10Plates
EUR 3270

Barritt Reagent A (for VP test)

R029-100ML 1 unit
EUR 6.48
Description: Barritt Reagent A (for VP test)

Barritt Reagent B (for VP test)

R030-100ML 1 unit
EUR 2.89
Description: Barritt Reagent B (for VP test)

RANGE 13 - Ventilated cabinet for reagents and toxic products - 250 L

MF4V each
EUR 2377.76

RANGE 13 - Cabinet for reagents and toxic products (without fan) - 250 L

MF4SV. each
EUR 2158.24

ImmunoGold labeling reagents for (TEM) - Unconjugated gold colloid (GC), 5nm

22716-100 100ml
EUR 1037.88
Description: 7732-18-5

ImmunoGold labeling reagents for (TEM) - Unconjugated gold colloid (GC), 10nm

22717-100 100ml
EUR 1022.76
Description: 7732-18-5

ImmunoGold labeling reagents for (TEM) - Unconjugated gold colloid (GC), 15nm

22718-100 100ml
EUR 1023.84
Description: 7732-18-5

ImmunoGold labeling reagents for (SEM) - Unconjugated gold colloid (GC) 20nm

22719-100 100ml
EUR 1036.8

COMBI IC Reagent: Mouse anti CD45 (FITC) and Mouse anti CD14 (PE)

MBS570370-50Tests 50Tests
EUR 450

COMBI IC Reagent: Mouse anti CD45 (FITC) and Mouse anti CD14 (PE)

MBS570370-5x50Tests 5x50Tests
EUR 1885

Amersham ECL Western Blotting Detection Reagents for 4000cm2 membrane - EACH

RPN2106 EACH
EUR 421.2

Amersham ECL Western Blotting Detection Reagents for 1000cm2 membrane - EACH

RPN2109 EACH
EUR 211.95

Amersham ECL Western Blotting Detection Reagents for 6000cm2 membrane - 1KIT

RPN2134 1KIT
EUR 643.95

Amersham ECL Western Blotting Detection Reagents for 2000cm2 membrane - EACH

RPN2209 EACH
EUR 328.05

T7 gRNA SmartNuclease Synthesis Kit (includes CAS510A-1 & T7 IVT synthesis reagents)

CAS510A-KIT 1 Kit
EUR 724

Low-density Lipoprotein Cholesterol -LDL-C- Colorimetric Assay Kit -Double Reagents-

E-BC-K205-96T 96T
EUR 150
Description: Quantitative

Low-density Lipoprotein Cholesterol -LDL-C- Colorimetric Assay Kit -Double Reagents-

E-BC-K205-each each Ask for price
Description: Quantitative

Low-density Lipoprotein Cholesterol -LDL-C- Colorimetric Assay Kit -Double Reagents-

E-BC-K206-S-100Assays 100 Assays
EUR 240
Description: Quantitative

Low-density Lipoprotein Cholesterol -LDL-C- Colorimetric Assay Kit -Double Reagents-

E-BC-K206-S-each each Ask for price
Description: Quantitative

High-density Lipoprotein Cholesterol -HDL-C- Colorimetric Assay Kit -Double reagents-

E-BC-K221-96T 96T
EUR 150
Description: Quantitative

High-density Lipoprotein Cholesterol -HDL-C- Colorimetric Assay Kit -Double reagents-

E-BC-K221-each each Ask for price
Description: Quantitative

High-density Lipoprotein Cholesterol -HDL-C- Colorimetric Assay Kit -Double reagents-

E-BC-K222-S-100Assays 100 Assays
EUR 240
Description: Quantitative

High-density Lipoprotein Cholesterol -HDL-C- Colorimetric Assay Kit -Double reagents-

E-BC-K222-S-each each Ask for price
Description: Quantitative

RPE REFERENCE STANDARD Reagent

GWB-Q00331 100 TESTS Ask for price

STREPTAVIDIN: RPE-Cy5.5 Reagent

GWB-Q00339 0.5 mg Ask for price

STREPTAVIDIN: RPE-Cy5.5 Reagent

GWB-Q00340 0.1 mg Ask for price

STREPTAVIDIN: RPE-Cy7 Reagent

GWB-Q00341 0.5 mg Ask for price

STREPTAVIDIN: RPE-Cy7 Reagent

GWB-Q00342 0.1 mg Ask for price

Reagents for the identification and qualitative measurement of anti-Zika NS1 antibodies.

ELS61258 3 x 96 well plate kit
EUR 641.21
Description: Zika Virus Total Antibody ELISA

Exo-Flow 2.0 Basic Kit without antibody (Streptavidin beads + reagents) - for Serum or Plasma

EXOFLOW2-BASICA-SP 30 rxn
EUR 1201.2

COMBI IC Reagent: Mouse anti Myeloperoxidase-C2 (FITC) and Mouse anti CD22 (PE)

MBS570348-1mL 1mL
EUR 615

COMBI IC Reagent: Mouse anti Myeloperoxidase-C2 (FITC) and Mouse anti CD22 (PE)

MBS570348-5x1mL 5x1mL
EUR 2620

Exo-Flow 2.0 Basic Kit without antibody (Streptavidin beads + reagents) - for Tissue Culture Media

EXOFLOW2-BASICA-TC 30 rxn
EUR 1201.2

cAMP Biotrak(TM) EIA; (Non-Acetylation Protocol; Lysis Reagents not Included); Cytiva; RPN2251 - EACH

GERPN2251 EACH
EUR 770.85

CD3 (FITC) CD20 (RPE) Antibody

GWB-Q01590 50 TESTS Ask for price

COMBI IC Reagent: Mouse anti Myeloperoxidase-C2 (FITC) and Mouse anti CD3 (PE)

MBS570355-1mL 1mL
EUR 615

COMBI IC Reagent: Mouse anti Myeloperoxidase-C2 (FITC) and Mouse anti CD3 (PE)

MBS570355-5x1mL 5x1mL
EUR 2620

STREPTAVIDIN: FITC Reagent

GWB-Q00335 1 mg Ask for price

QUANTUM FITC-5 MESF Reagent

GWB-Q00318 20 TESTS Ask for price

QUANTUM FITC-5 MESF Reagent

GWB-Q00319 100 TESTS Ask for price

QUANTUM FITC-5 MESF Reagent

GWB-Q00320 280 TESTS Ask for price

OOSA09633-100T - RPE REFERENCE STANDARD Accessory Reagent

OOSA09633-100T 100Tests
EUR 889

TruStrip WBV Tubulin protein quantitation & Western Blot Validation Kit (contains actin strips, primary antibodies and Western reagents 100 strips or 10 miniblot)

WBTUB100-K 1 Kit
EUR 634.8

COMBI IC Reagent: IgG Negative Control (FITC) and IgG Negative Control (PE)

MBS570400-1mL 1mL
EUR 370

COMBI IC Reagent: IgG Negative Control (FITC) and IgG Negative Control (PE)

MBS570400-5x1mL 5x1mL
EUR 1525

COMBI IC Reagent: Mouse anti Lysozyme (FITC) and Mouse anti Lactoferrin (PE)

MBS570350-1mL 1mL
EUR 615

COMBI IC Reagent: Mouse anti Lysozyme (FITC) and Mouse anti Lactoferrin (PE)

MBS570350-5x1mL 5x1mL
EUR 2620

TruStrip WBV Human Beta Actin Protein Quantitation & Western Blot Validation Kit (contains actin strips, primary antibodies and Western reagents 100 strips or 10 miniblot)

WBACT100-K 1 Kit
EUR 634.8

OOSA09643-280T - RPE-TR REFERENCE STANDARD Accessory Reagent

OOSA09643-280T 280Tests
EUR 429

OOSA09640-280T - RPE-Cy5 REFERENCE STANDARD Accessory Reagent

OOSA09640-280T 280Tests
EUR 429

QUANTUM FITC-5 MESF (PRE-MIXED) Reagent

GWB-Q00321 20 TESTS Ask for price

QUANTUM FITC-5 MESF (PRE-MIXED) Reagent

GWB-Q00322 100 TESTS Ask for price

COMBI IC Reagent: Mouse anti Myeloperoxidase-C2 (FITC) and Mouse anti Lactoferrin (PE)

MBS570364-1mL 1mL
EUR 615

COMBI IC Reagent: Mouse anti Myeloperoxidase-C2 (FITC) and Mouse anti Lactoferrin (PE)

MBS570364-5x1mL 5x1mL
EUR 2620

 

Engineering caspase 7 as an affinity reagent to capture proteolytic products

Many proteases recognize their substrates with high specificities, with this in mind, it should theoretically be possible to utilize the substrate binding cleft of a protease as a scaffold to engineer an affinity reagent. In this study, we sought to develop reagents that would differentiate between substrates and products of proteolysis, based on a caspase 7 scaffold. Firstly, we engineered a form of caspase 7 that can undergo conversion to a substrate binding conformation without catalysis. Seeking to generate a product-only trap, we further engineered this construct by incorporating mutations that compensate for the generation of a negative charge in the neo C terminus of a newly generated product.
  • This was accomplished with only three substitutions within the substrate binding cleft. Moreover, the affinity of the product trap for peptides was comparable to the affinity of caspase 7 to parental substrates.
  • Finally, generation of a hybrid fluorescent protein with the product trap provided a reagent that specifically recognized apoptotic cells and highlights the versatility of such an approach in developing affinity and imaging agents for a variety of cysteine and serine proteases.

Leveraging nature’s biomolecular designs in next-generation protein sequencing reagent development

Next-generation approaches for protein sequencing are now emerging that could have the potential to revolutionize the field in proteomics. One such sequencing method involves fluorescence-based imaging of immobilized peptides in which the N-terminal amino acid of a polypeptide is readout sequentially by a series of fluorescently labeled biomolecules.

When selectively bound to a specific N-terminal amino acid, the NAAB (N-terminal amino acid binder) affinity reagent identifies the amino acid through its associated fluorescence tag. A key technical challenge in implementing this fluoro-sequencing approach is the need to develop NAAB affinity reagents with the high affinity and selectivity for specific N-terminal amino acids required for this biotechnology application.

One approach to develop such a NAAB affinity reagent is to leverage naturally occurring biomolecules that bind amino acids and/or peptides. Here, we describe several candidate biomolecules that could be considered for this purpose and discuss the potential for developability of each.

Key points • Next-generation sequencing methods are emerging that could revolutionize proteomics. • Sequential readout of N-terminal amino acids by fluorescent-tagged affinity reagents. • Native peptide/amino acid binders can be engineered into affinity reagents. • Protein size and structure contribute to feasibility of reagent developability.

3-Epikatonic acid

TN2931-1mg 1mg Ask for price
Description: 3-Epikatonic acid

3-Epikatonic acid

TN2931-50mg 50mg Ask for price
Description: 3-Epikatonic acid

3-Epikatonic acid

TN2931-5mg 5mg Ask for price
Description: 3-Epikatonic acid

16-Epikoumidine

TTE1328 unit Ask for price

16-Epikoumidine

TN6036-10mg 10mg Ask for price
Description: 16-Epikoumidine

16-Epikoumidine

TN6036-1g 1g Ask for price
Description: 16-Epikoumidine

16-Epikoumidine

TN6036-1mg 1mg Ask for price
Description: 16-Epikoumidine

16-Epikoumidine

TN6036-50mg 50mg Ask for price
Description: 16-Epikoumidine

16-Epikoumidine

TN6036-5mg 5mg Ask for price
Description: 16-Epikoumidine

3-Epikarounidiol

TBZ1276 unit Ask for price

PI3KC3, CT (E785) (PIK3C3, VPS34, Phosphatidylinositol 3-kinase catalytic subunit type 3, Phosphatidylinositol 3-kinase p100 subunit, Phosphoinositide-3-kinase class 3, hVps34) (AP)

MBS6333596-02mL 0.2mL
EUR 980

PI3KC3, CT (E785) (PIK3C3, VPS34, Phosphatidylinositol 3-kinase catalytic subunit type 3, Phosphatidylinositol 3-kinase p100 subunit, Phosphoinositide-3-kinase class 3, hVps34) (AP)

MBS6333596-5x02mL 5x0.2mL
EUR 4250

PI3KC3, CT (E785) (PIK3C3, VPS34, Phosphatidylinositol 3-kinase catalytic subunit type 3, Phosphatidylinositol 3-kinase p100 subunit, Phosphoinositide-3-kinase class 3, hVps34) (APC)

MBS6333597-02mL 0.2mL
EUR 980

PI3KC3, CT (E785) (PIK3C3, VPS34, Phosphatidylinositol 3-kinase catalytic subunit type 3, Phosphatidylinositol 3-kinase p100 subunit, Phosphoinositide-3-kinase class 3, hVps34) (APC)

MBS6333597-5x02mL 5x0.2mL
EUR 4250

PI3KC3, CT (E785) (PIK3C3, VPS34, Phosphatidylinositol 3-kinase catalytic subunit type 3, Phosphatidylinositol 3-kinase p100 subunit, Phosphoinositide-3-kinase class 3, hVps34) (FITC)

MBS6333599-02mL 0.2mL
EUR 980

PI3KC3, CT (E785) (PIK3C3, VPS34, Phosphatidylinositol 3-kinase catalytic subunit type 3, Phosphatidylinositol 3-kinase p100 subunit, Phosphoinositide-3-kinase class 3, hVps34) (FITC)

MBS6333599-5x02mL 5x0.2mL
EUR 4250

PI3KC3, CT (E785) (PIK3C3, VPS34, Phosphatidylinositol 3-kinase catalytic subunit type 3, Phosphatidylinositol 3-kinase p100 subunit, Phosphoinositide-3-kinase class 3, hVps34) (PE)

MBS6333606-02mL 0.2mL
EUR 980

PI3KC3, CT (E785) (PIK3C3, VPS34, Phosphatidylinositol 3-kinase catalytic subunit type 3, Phosphatidylinositol 3-kinase p100 subunit, Phosphoinositide-3-kinase class 3, hVps34) (PE)

MBS6333606-5x02mL 5x0.2mL
EUR 4250

PI3KC3, CT (E785) (PIK3C3, VPS34, Phosphatidylinositol 3-kinase catalytic subunit type 3, Phosphatidylinositol 3-kinase p100 subunit, Phosphoinositide-3-kinase class 3, hVps34)

MBS6005618-02mL 0.2(mL
EUR 695

PI3KC3, CT (E785) (PIK3C3, VPS34, Phosphatidylinositol 3-kinase catalytic subunit type 3, Phosphatidylinositol 3-kinase p100 subunit, Phosphoinositide-3-kinase class 3, hVps34)

MBS6005618-5x02mL 5x0.2mL
EUR 2975

Influenza A/Duck/Egypt/AR526/2017 (EPI_ISL_344529) nucleoprotein (EPI1420358)

REC32058-100 0.1
EUR 280.67
Description: Influenza A/Duck/Egypt/AR526/2017 (EPI_ISL_344529) nucleoprotein (EPI1420358)

Influenza A/Duck/Egypt/AR526/2017 (EPI_ISL_344529) nucleoprotein (EPI1420358)

REC32058-500 0.5
EUR 1182.63
Description: Influenza A/Duck/Egypt/AR526/2017 (EPI_ISL_344529) nucleoprotein (EPI1420358)

Influenza A/chicken/Scotland/054477/2021 (EPI_ISL_9012696) nucleoprotein (EPI1963385)

REC32055-100 0.1
EUR 311.28
Description: Influenza A/chicken/Scotland/054477/2021 (EPI_ISL_9012696) nucleoprotein (EPI1963385)

Influenza A/chicken/Scotland/054477/2021 (EPI_ISL_9012696) nucleoprotein (EPI1963385)

REC32055-500 0.5
EUR 1182.63
Description: Influenza A/chicken/Scotland/054477/2021 (EPI_ISL_9012696) nucleoprotein (EPI1963385)

Influenza A/Greylag_goose/England/054503/2021 (EPI_ISL_9029965) nucleoprotein (EPI1963898)

REC32056-100 0.1
EUR 311.28
Description: Influenza A/Greylag_goose/England/054503/2021 (EPI_ISL_9029965) nucleoprotein (EPI1963898)

Influenza A/Greylag_goose/England/054503/2021 (EPI_ISL_9029965) nucleoprotein (EPI1963898)

REC32056-500 0.5
EUR 1182.63
Description: Influenza A/Greylag_goose/England/054503/2021 (EPI_ISL_9029965) nucleoprotein (EPI1963898)

Influenza A/Cambodia/NPH230032/2023 (EPI_ISL_17024123) nucleoprotein (EPI2419703)

REC32059-100 0.1
EUR 280.67
Description: Influenza A/Cambodia/NPH230032/2023 (EPI_ISL_17024123) nucleoprotein (EPI2419703)

Influenza A/Cambodia/NPH230032/2023 (EPI_ISL_17024123) nucleoprotein (EPI2419703)

REC32059-500 0.5
EUR 1182.63
Description: Influenza A/Cambodia/NPH230032/2023 (EPI_ISL_17024123) nucleoprotein (EPI2419703)

Influenza A/Greylag_goose/Scotland/024915/2022 (EPI_ISL_13486869) nucleoprotein (EPI2076366)

REC32057-100 0.1
EUR 280.67
Description: Influenza A/Greylag_goose/Scotland/024915/2022 (EPI_ISL_13486869) nucleoprotein (EPI2076366)

Influenza A/Greylag_goose/Scotland/024915/2022 (EPI_ISL_13486869) nucleoprotein (EPI2076366)

REC32057-500 0.5
EUR 1182.63
Description: Influenza A/Greylag_goose/Scotland/024915/2022 (EPI_ISL_13486869) nucleoprotein (EPI2076366)

Influenza A/Greylag_goose/Scotland/024915/2022 (EPI_ISL_13486869) hemagglutinin (EPI2076373)

REC32060-100 0.1
EUR 298.53
Description:
Influenza A/Greylag_goose/Scotland/024915/2022 hemagglutinin, C-terminally tagged with a T4 fooldon domain to stabilize trimer s.

Influenza A/Greylag_goose/Scotland/024915/2022 (EPI_ISL_13486869) hemagglutinin (EPI2076373)

REC32060-500 0.5
EUR 1047.4
Description:
Influenza A/Greylag_goose/Scotland/024915/2022 hemagglutinin, C-terminally tagged with a T4 fooldon domain to stabilize trimer s.

Influenza A/Greylag_goose/Scotland/024915/2022 (EPI_ISL_13486869) neuraminidase (EPI2076372)

REC32061-100 0.1
EUR 298.53
Description:
Influenza A/Greylag_goose/Scotland/024915/2022 (EPI_ISL_13486869) neuraminidase (EPI2076372), expressed in HEK293 cells and purified from culture supernatant. The protein is stabilized as a tetramer via an N-terminal tetrabrachion domain

Influenza A/Greylag_goose/Scotland/024915/2022 (EPI_ISL_13486869) neuraminidase (EPI2076372)

REC32061-500 0.5
EUR 1047.4
Description:
Influenza A/Greylag_goose/Scotland/024915/2022 (EPI_ISL_13486869) neuraminidase (EPI2076372), expressed in HEK293 cells and purified from culture supernatant. The protein is stabilized as a tetramer via an N-terminal tetrabrachion domain

EPI-7170

HY-150102 10 mg
EUR 1590.93
Description: EPI-7170, a ralaniten analogue, is a potent androgen receptor N-terminal structural domain antagonist that blocks the transcriptional activity of full-length AR (FL-AR) and AR splice variants (AR-Vs). EPI-7170 has antitumor effects against enzalutamide resistant castration-resistant prostate cancer (CRPC)[1].

EPI-7170

T63811-10mg 10mg Ask for price
Description: EPI-7170

EPI-7170

T63811-1g 1g Ask for price
Description: EPI-7170

EPI-7170

T63811-1mg 1mg Ask for price
Description: EPI-7170

EPI-7170

T63811-50mg 50mg Ask for price
Description: EPI-7170

EPI-7170

T63811-5mg 5mg Ask for price
Description: EPI-7170

PI3KC3, CT (E785) (PIK3C3, VPS34, Phosphatidylinositol 3-kinase catalytic subunit type 3, Phosphatidylinositol 3-kinase p100 subunit, Phosphoinositide-3-kinase class 3, hVps34) (Biotin)

MBS6333598-02mL 0.2mL
EUR 980

PI3KC3, CT (E785) (PIK3C3, VPS34, Phosphatidylinositol 3-kinase catalytic subunit type 3, Phosphatidylinositol 3-kinase p100 subunit, Phosphoinositide-3-kinase class 3, hVps34) (Biotin)

MBS6333598-5x02mL 5x0.2mL
EUR 4250

PI3KC3, CT (E785) (PIK3C3, VPS34, Phosphatidylinositol 3-kinase catalytic subunit type 3, Phosphatidylinositol 3-kinase p100 subunit, Phosphoinositide-3-kinase class 3, hVps34) (Azide free) (HRP)

MBS6333600-02mL 0.2mL
EUR 980

PI3KC3, CT (E785) (PIK3C3, VPS34, Phosphatidylinositol 3-kinase catalytic subunit type 3, Phosphatidylinositol 3-kinase p100 subunit, Phosphoinositide-3-kinase class 3, hVps34) (Azide free) (HRP)

MBS6333600-5x02mL 5x0.2mL
EUR 4250

PI3KC3, CT (E785) (PIK3C3, VPS34, Phosphatidylinositol 3-kinase catalytic subunit type 3, Phosphatidylinositol 3-kinase p100 subunit, Phosphoinositide-3-kinase class 3, hVps34) (MaxLight 405)

MBS6333601-01mL 0.1mL
EUR 980

PI3KC3, CT (E785) (PIK3C3, VPS34, Phosphatidylinositol 3-kinase catalytic subunit type 3, Phosphatidylinositol 3-kinase p100 subunit, Phosphoinositide-3-kinase class 3, hVps34) (MaxLight 405)

MBS6333601-5x01mL 5x0.1mL
EUR 4250

PI3KC3, CT (E785) (PIK3C3, VPS34, Phosphatidylinositol 3-kinase catalytic subunit type 3, Phosphatidylinositol 3-kinase p100 subunit, Phosphoinositide-3-kinase class 3, hVps34) (MaxLight 490)

MBS6333602-01mL 0.1mL
EUR 980

PI3KC3, CT (E785) (PIK3C3, VPS34, Phosphatidylinositol 3-kinase catalytic subunit type 3, Phosphatidylinositol 3-kinase p100 subunit, Phosphoinositide-3-kinase class 3, hVps34) (MaxLight 490)

MBS6333602-5x01mL 5x0.1mL
EUR 4250

PI3KC3, CT (E785) (PIK3C3, VPS34, Phosphatidylinositol 3-kinase catalytic subunit type 3, Phosphatidylinositol 3-kinase p100 subunit, Phosphoinositide-3-kinase class 3, hVps34) (MaxLight 550)

MBS6333603-01mL 0.1mL
EUR 980

PI3KC3, CT (E785) (PIK3C3, VPS34, Phosphatidylinositol 3-kinase catalytic subunit type 3, Phosphatidylinositol 3-kinase p100 subunit, Phosphoinositide-3-kinase class 3, hVps34) (MaxLight 550)

MBS6333603-5x01mL 5x0.1mL
EUR 4250

PI3KC3, CT (E785) (PIK3C3, VPS34, Phosphatidylinositol 3-kinase catalytic subunit type 3, Phosphatidylinositol 3-kinase p100 subunit, Phosphoinositide-3-kinase class 3, hVps34) (MaxLight 650)

MBS6333604-01mL 0.1mL
EUR 980

PI3KC3, CT (E785) (PIK3C3, VPS34, Phosphatidylinositol 3-kinase catalytic subunit type 3, Phosphatidylinositol 3-kinase p100 subunit, Phosphoinositide-3-kinase class 3, hVps34) (MaxLight 650)

MBS6333604-5x01mL 5x0.1mL
EUR 4250

PI3KC3, CT (E785) (PIK3C3, VPS34, Phosphatidylinositol 3-kinase catalytic subunit type 3, Phosphatidylinositol 3-kinase p100 subunit, Phosphoinositide-3-kinase class 3, hVps34) (MaxLight 750)

MBS6333605-01mL 0.1mL
EUR 980

PI3KC3, CT (E785) (PIK3C3, VPS34, Phosphatidylinositol 3-kinase catalytic subunit type 3, Phosphatidylinositol 3-kinase p100 subunit, Phosphoinositide-3-kinase class 3, hVps34) (MaxLight 750)

MBS6333605-5x01mL 5x0.1mL
EUR 4250

EPI-001

555572 10.0mg
EUR 250

EPI-001

B6041-10 10 mg
EUR 56
Description: Endocrinology and Hormones|Androgen Receptor

EPI-001

B6041-200 200 mg
EUR 376
Description: Endocrinology and Hormones|Androgen Receptor

EPI-001

B6041-50 50 mg
EUR 168
Description: Endocrinology and Hormones|Androgen Receptor

EPI-001

MBS131396-100mg 100mg
EUR 1495

EPI-001

HY-100348 10 mg
EUR 333.34
Description: EPI-001, a selective inhibitor of Androgen Receptor (AR), targets transactivation unit 5 (Tau-5) of the AR. EPI-001 can inhibit transactivation of the AR amino-terminal domain (NTD), with an IC50 of ~6 μM. EPI-001 is also a selective modulator of PPARγ. EPI-001 is active against castration-resistant prostate cancer[1][2][3].

EPI-743

HY-16772 10 mg
EUR 1028.15
Description: EPI-743 (Vatiquinone; α-Tocotrienol quinone; PTC-743; NCT04378075) is a potent cellular oxidative stress protectant, inhibits ferroptosis in cells, which could be used for the study for mitochondrial diseases. EPI-743 is a synthetic analog of vitamin E with oral activity, targets repletion of reduced intracellular glutathione[1][2].

EPI-589

HY-125999 10 mg
EUR 432.91
Description: EPI-589, a quinone derivative, is a safe and well tolerated oxidoreductase enzyme inhibitor. EPI-589 has the potential for the treatment of amyotrophic lateral sclerosis (ALS)[1].

EPI-589

MBS5766602-5mg 5mg
EUR 915

EPI-589

MBS5766602-5x5mg 5x5mg
EUR 3970

EPI-001

MBS384678-10mg 10mg
EUR 160

EPI-001

MBS384678-25mg 25mg
EUR 240

EPI-001

MBS384678-50mg 50mg
EUR 300

EPI-001

MBS384678-5x50mg 5x50mg
EUR 1340

EPI-589

T11214-10mg 10mg Ask for price
Description: EPI-589

EPI-589

T11214-1g 1g Ask for price
Description: EPI-589

EPI-589

T11214-1mg 1mg Ask for price
Description: EPI-589

EPI-589

T11214-50mg 50mg Ask for price
Description: EPI-589

EPI-589

T11214-5mg 5mg Ask for price
Description: EPI-589

EPI-001

T6829-10mg 10mg Ask for price
Description: EPI-001

EPI-001

T6829-1g 1g Ask for price
Description: EPI-001

EPI-001

T6829-1mg 1mg Ask for price
Description: EPI-001

EPI-001

T6829-50mg 50mg Ask for price
Description: EPI-001

EPI-001

T6829-5mg 5mg Ask for price
Description: EPI-001

Influenza A/Sydney/5/2021 (H1N1)pdm09-like virus HA (EPI1942222), C-terminal T4 foldon, His-tag

REC32038-100 0.1
EUR 301.29
Description: Influenza A/Sydney/5/2021 (H1N1)pdm09-like virus HA (EPI1942222), C-terminal T4 foldon, His-tag. This product is part of the WHO vaccine composition recommendation for influenza virus for the Southern hemisphere 2023.

Influenza A/Sydney/5/2021 (H1N1)pdm09-like virus HA (EPI1942222), C-terminal T4 foldon, His-tag

REC32038-500 0.5
EUR 1057.09
Description: Influenza A/Sydney/5/2021 (H1N1)pdm09-like virus HA (EPI1942222), C-terminal T4 foldon, His-tag. This product is part of the WHO vaccine composition recommendation for influenza virus for the Southern hemisphere 2023.

Influenza A/Sydney/5/2021 (H1N1)pdm09-like virus HA (EPI1957293), C-terminal T4 foldon, His-tag

REC32039-100 0.1
EUR 301.29
Description: Influenza A/Sydney/5/2021 (H1N1)pdm09-like virus HA (EPI1957293), C-terminal T4 foldon, His-tag. This product is part of the WHO vaccine composition recommendation for influenza virus for the Southern hemisphere 2023.

Influenza A/Sydney/5/2021 (H1N1)pdm09-like virus HA (EPI1957293), C-terminal T4 foldon, His-tag

REC32039-500 0.5
EUR 1057.09
Description: Influenza A/Sydney/5/2021 (H1N1)pdm09-like virus HA (EPI1957293), C-terminal T4 foldon, His-tag. This product is part of the WHO vaccine composition recommendation for influenza virus for the Southern hemisphere 2023.

EPI300 Escherichia coli Strains

S0050 100 ul
EUR 438

EPI400 Escherichia coli Strains

S0087 100 ul
EUR 438

41210-2 RB EPIDIDYMUS YG 50 EA

41210-2 50 EA
EUR 383