Cross-Couplings between Alkyl Halides and Grignard Reagents
Cobalt-Catalyzed Cross-Couplings between Alkyl Halides and Grignard Reagents
- Together with these economical and environmental considerations, the 3d metallic catalysts moreover exhibit complementary reactivity with palladium complexes, facilitating utilizing alkyl halide companions attributable to the decrease of β-elimination side reactions.
- Particularly, by using cobalt catalysts, fairly just a few cross-couplings between alkyl halides and organometallics have been described.
- Nonetheless, cobalt catalysis nonetheless stays far behind palladium catalysis with regards to fame and functions, and the enlargement of the substrate scope along with the occasion of easy and durable catalytic packages stays an needed drawback.
- In 2012, our group entered the cobalt catalysis space by rising a cobalt-catalyzed cross-coupling between C-bromo glycosides and Grignard reagents. The generality of the coupling allowed the preparation of a wide range of useful C-aryl and C-vinyl glycoside establishing blocks.
- We then centered on the functionalization of saturated N-heterocycles, and various halo-azetidines, -pyrrolidines, and -piperidines had been effectively reacted with aryl and alkenyl Grignard reagents beneath cobalt catalysis.
- With the goal of creating prepared useful α-aryl amides, a cobalt-catalyzed cross-coupling utilized to α-bromo amides was studied after which extended to α-bromo lactams.
- These days, we moreover reported an setting pleasant and regular cross-coupling involving cyclopropyl- and cyclobutyl-magnesium bromides. This technique permits the alkylation of functionalized small strained rings by a wide range of main and secondary alkyl halides.

gentaur
![]() EZ-DNA Reagents |
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BS8202 | Bio Basic | 100preps | EUR 88.06 |
![]() EZ-DNA Reagents |
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SK8201 | Bio Basic | 100preps | EUR 93.5 |
![]() BI 6727 |
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2222-1 | Biovision | EUR 120 |
![]() BI 6727 |
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2222-5 | Biovision | EUR 327 |
![]() BI-2536 |
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2370-25 | Biovision | EUR 523 |
![]() BI-2536 |
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2370-5 | Biovision | EUR 175 |
![]() BI-D1870 |
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1924-1 | Biovision | EUR 142 |
![]() BI-D1870 |
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1924-5 | Biovision | EUR 370 |
![]() BI-78D3 |
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B1686-25 | Biovision | EUR 528 |
![]() BI-78D3 |
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B1686-5 | Biovision | EUR 175 |
![]() BI-7273 |
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B1879-25 | Biovision | EUR 892 |
![]() BI-7273 |
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B1879-5 | Biovision | EUR 262 |
![]() BI-9564 |
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B1880-25 | Biovision | EUR 756 |
![]() BI-9564 |
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B1880-5 | Biovision | EUR 229 |
![]() BI-409306 |
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B2377-25 | Biovision | EUR 756 |
![]() BI-409306 |
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B2377-5 | Biovision | EUR 229 |
![]() BI-9627 |
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HY-18071 | MedChemExpress | 5mg | EUR 291 |
![]() BI 224436 |
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HY-18595 | MedChemExpress | 5mg | EUR 533 |
![]() (±)-BI-D |
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HY-18601 | MedChemExpress | 100mg | EUR 2943 |
![]() BI-847325 |
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HY-18955 | MedChemExpress | 100mg | EUR 1262 |
![]() BI 2536 |
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HY-50698 | MedChemExpress | 100mg | EUR 1229 |
![]() BI-78D3 |
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HY-10366 | MedChemExpress | 25mg | EUR 349 |
![]() BI-6C9 |
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HY-103661 | MedChemExpress | 50mg | EUR 1083 |
![]() BI-D1870 |
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HY-10510 | MedChemExpress | 2mg | EUR 147 |
![]() BI-882370 |
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HY-107779 | MedChemExpress | 100mg | EUR 1164 |
![]() BI-3802 |
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HY-108705 | MedChemExpress | 10mg | EUR 911 |
![]() BI-3812 |
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HY-111381 | MedChemExpress | 25mg | EUR 1772 |
![]() BI-3663 |
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HY-111546 | MedChemExpress | 1mg | EUR 681 |
![]() BI-749327 |
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HY-111925 | MedChemExpress | 100mg | EUR 3092 |
![]() BI-409306 |
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HY-112831 | MedChemExpress | 50mg | EUR 2058 |
![]() BI-671800 |
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HY-114141 | MedChemExpress | 100mg | EUR 3092 |
![]() BI-1347 |
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HY-120350 | MedChemExpress | 10mM/1mL | EUR 176 |
![]() BI-167107 |
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HY-121251 | MedChemExpress | 100mg | EUR 2633 |
![]() BI-4464 |
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HY-124625 | MedChemExpress | 10mg | EUR 911 |
![]() BI 01383298 |
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HY-124738 | MedChemExpress | 10mM/1mL | EUR 163 |
![]() BI-4020 |
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HY-129550 | MedChemExpress | 10mg | EUR 681 |
![]() BI-7273 |
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HY-100351 | MedChemExpress | 50mg | EUR 877 |
![]() BI-9564 |
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HY-100352 | MedChemExpress | 200mg | EUR 2254 |
![]() BI 689648 |
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HY-101217 | MedChemExpress | 25mg | EUR 2116 |
![]() BI 78D3 |
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B9011-10 | ApexBio | 10 mg | EUR 216 |
Description: BI-78D3 is a substrate competitive inhibitor of JNK inhibitor [2].JNK is a member of the MAPK family. JNK is a stress-activated protein kinase that modulates pathways implicated in a variety of disease states. |
![]() BI 78D3 |
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B9011-100 | ApexBio | 100 mg | EUR 1094 |
Description: BI-78D3 is a substrate competitive inhibitor of JNK inhibitor [2].JNK is a member of the MAPK family. JNK is a stress-activated protein kinase that modulates pathways implicated in a variety of disease states. |
![]() BI 78D3 |
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B9011-25 | ApexBio | 25 mg | EUR 412 |
Description: BI-78D3 is a substrate competitive inhibitor of JNK inhibitor [2].JNK is a member of the MAPK family. JNK is a stress-activated protein kinase that modulates pathways implicated in a variety of disease states. |
![]() BI 78D3 |
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B9011-5 | ApexBio | 5 mg | EUR 161 |
Description: BI-78D3 is a substrate competitive inhibitor of JNK inhibitor [2].JNK is a member of the MAPK family. JNK is a stress-activated protein kinase that modulates pathways implicated in a variety of disease states. |
![]() BI 78D3 |
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B9011-5.1 | ApexBio | 10 mM (in 1mL DMSO) | EUR 183 |
Description: BI-78D3 is a substrate competitive inhibitor of JNK inhibitor [2].JNK is a member of the MAPK family. JNK is a stress-activated protein kinase that modulates pathways implicated in a variety of disease states. |
![]() BI 78D3 |
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B9011-50 | ApexBio | 50 mg | EUR 676 |
Description: BI-78D3 is a substrate competitive inhibitor of JNK inhibitor [2].JNK is a member of the MAPK family. JNK is a stress-activated protein kinase that modulates pathways implicated in a variety of disease states. |
![]() BI 2536 |
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A3965-10 | ApexBio | 10 mg | EUR 224 |
Description: BI 2536 is a potent, ATP-competitive, well tolerated and highly specific human polo-like kinase 1 (PLK1) inhibitor with IC value of 0.83 nM, which shows 1000-fold selectivity against other kinases [1]. |
![]() BI 2536 |
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A3965-5 | ApexBio | 5 mg | EUR 148 |
Description: BI 2536 is a potent, ATP-competitive, well tolerated and highly specific human polo-like kinase 1 (PLK1) inhibitor with IC value of 0.83 nM, which shows 1000-fold selectivity against other kinases [1]. |
![]() BI 2536 |
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A3965-5.1 | ApexBio | 10 mM (in 1mL DMSO) | EUR 195 |
Description: BI 2536 is a potent, ATP-competitive, well tolerated and highly specific human polo-like kinase 1 (PLK1) inhibitor with IC value of 0.83 nM, which shows 1000-fold selectivity against other kinases [1]. |
![]() BI 2536 |
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A3965-50 | ApexBio | 50 mg | EUR 595 |
Description: BI 2536 is a potent, ATP-competitive, well tolerated and highly specific human polo-like kinase 1 (PLK1) inhibitor with IC value of 0.83 nM, which shows 1000-fold selectivity against other kinases [1]. |
![]() BI 2536 |
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A3965-S | ApexBio | Evaluation Sample | EUR 81 |
Description: BI 2536 is a potent, ATP-competitive, well tolerated and highly specific human polo-like kinase 1 (PLK1) inhibitor with IC value of 0.83 nM, which shows 1000-fold selectivity against other kinases [1]. |
![]() BI 6015 |
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B5668-10 | ApexBio | 10 mg | EUR 179 |
Description: BI 6015 is an antagonist of hepatocyte nuclear factor 4? [1]. Hepatocyte nuclear factor 4? (HNF4?) is a nuclear receptor and regulates gene expression in enterocytes, hepatocytes and pancreatic ? cells [1]. BI 6015 is a HNF4? antagonist. |
![]() BI 6015 |
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B5668-5 | ApexBio | 5 mg | EUR 118 |
Description: BI 6015 is an antagonist of hepatocyte nuclear factor 4? [1]. Hepatocyte nuclear factor 4? (HNF4?) is a nuclear receptor and regulates gene expression in enterocytes, hepatocytes and pancreatic ? cells [1]. BI 6015 is a HNF4? antagonist. |
![]() BI 6015 |
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B5668-50 | ApexBio | 50 mg | EUR 595 |
Description: BI 6015 is an antagonist of hepatocyte nuclear factor 4? [1]. Hepatocyte nuclear factor 4? (HNF4?) is a nuclear receptor and regulates gene expression in enterocytes, hepatocytes and pancreatic ? cells [1]. BI 6015 is a HNF4? antagonist. |
![]() BI-847325 |
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B6014-1 | ApexBio | 1 mg | EUR 132 |
Description: BI 847325 is a dual inhibitor of Ras-mitogen-activated protein kinase kinases (MEK) and Aurora kinases [1,2]. BI 847325 inhibits MEK1 and MEK2 with IC50 values of 25 and 4 nM, respectively. |
![]() BI-847325 |
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B6014-5 | ApexBio | 5 mg | EUR 242 |
Description: BI 847325 is a dual inhibitor of Ras-mitogen-activated protein kinase kinases (MEK) and Aurora kinases [1,2]. BI 847325 inhibits MEK1 and MEK2 with IC50 values of 25 and 4 nM, respectively. |
![]() BI-9564 |
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B6184-1 | ApexBio | 1 mg | EUR 109 |
Description: IC50: 75 nM and 3.4 ?M for BRD9 and BRD7 bromodomains, respectivelyBI-9564 is a BRD9/7 specific inhibitor.BRD7 and BRD9 are two important members of the bromodomain family protein. |
![]() BI-9564 |
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B6184-10 | ApexBio | 10 mg | EUR 293 |
Description: IC50: 75 nM and 3.4 ?M for BRD9 and BRD7 bromodomains, respectivelyBI-9564 is a BRD9/7 specific inhibitor.BRD7 and BRD9 are two important members of the bromodomain family protein. |
![]() BI-D1870 |
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B2227-10 | ApexBio | 10 mg | EUR 270 |
Description: BI-D1870 is a cell-permeable inhibitor of the p90 RSK isoforms with IC50 values of 31nM, 24nM, 18nM and 15nM for RSK1, RSK2, RSK3 and RSK4 respectively [1].BI-D1870 is a derivative of dihydropteridinone and found to be a remarkably specific inhibitor of RSK isoforms. |
![]() BI-D1870 |
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B2227-5 | ApexBio | 5 mg | EUR 189 |
Description: BI-D1870 is a cell-permeable inhibitor of the p90 RSK isoforms with IC50 values of 31nM, 24nM, 18nM and 15nM for RSK1, RSK2, RSK3 and RSK4 respectively [1].BI-D1870 is a derivative of dihydropteridinone and found to be a remarkably specific inhibitor of RSK isoforms. |
![]() BI-D1870 |
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B2227-5.1 | ApexBio | 10 mM (in 1mL DMSO) | EUR 235 |
Description: BI-D1870 is a cell-permeable inhibitor of the p90 RSK isoforms with IC50 values of 31nM, 24nM, 18nM and 15nM for RSK1, RSK2, RSK3 and RSK4 respectively [1].BI-D1870 is a derivative of dihydropteridinone and found to be a remarkably specific inhibitor of RSK isoforms. |
![]() BI-D1870 |
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B2227-50 | ApexBio | 50 mg | EUR 595 |
Description: BI-D1870 is a cell-permeable inhibitor of the p90 RSK isoforms with IC50 values of 31nM, 24nM, 18nM and 15nM for RSK1, RSK2, RSK3 and RSK4 respectively [1].BI-D1870 is a derivative of dihydropteridinone and found to be a remarkably specific inhibitor of RSK isoforms. |
![]() BI-7273 |
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B6196-25 | ApexBio | 25 mg | EUR 437 |
Description: IC50: 19 and 117 nM for BRD9 and BRD7, respectively.BI-7273 is a BRD9 bromodomain inhibitor. |
![]() BI-7273 |
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B6196-5 | ApexBio | 5 mg | EUR 168 |
Description: IC50: 19 and 117 nM for BRD9 and BRD7, respectively.BI-7273 is a BRD9 bromodomain inhibitor. |
![]() Mouse IgG-PE conjugate (isotype control) |
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20008-PE | Alpha Diagnostics | 50 Tests | EUR 164 |
![]() Rabbit IgG-PE conjugate (isotype control) |
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20009-PE | Alpha Diagnostics | 100 tests | EUR 225 |
![]() Goat IgG-PE conjugate (isotype control) |
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20011-PE | Alpha Diagnostics | 100 tests | EUR 225 |
![]() Monoclonal Anti-Rat IgG1-PE Conjugate |
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50126-PE | Alpha Diagnostics | 0.1 ml | EUR 347 |
![]() Goat Anti-Camel IgG-RPE conjugate |
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30835-RPE | Alpha Diagnostics | 0.5 ml | EUR 263 |
![]() Set of 10 Biolipidure Reagents |
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Biolipidure-set | Biolipidure | 10mLx10 | EUR 1517 |
Description: Set of 10 Biolipidure Reagents, whose applications include Immunoassays, Western blots, Immunohistochemistry, Turbidimetric assays, Immunochromatography, and Bead based assays. Benefits include: No lot to lot variation, No animal derived materials, Non-specific adsorption suppression, Stabilization of immobilized antibody, Stabilization of enzyme-antibody conjugate, Enzyme-substrate reaction enhancement and aggregation reaction enhancement |
![]() Rat IgG-PE conjugate (isotype control) (Isotype control) |
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20005-PE | Alpha Diagnostics | 25 tests | EUR 202 |
![]() Anti-Human CD44 Monoclonal Antibody PE Conjugated, Flow Validated |
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FC00052-PE | BosterBio | 25 Tests, 100 Tests, 200 Tests | EUR 153 |
Description: Mouse Monoclonal Human CD44 Antibody PE Conjugated, Flow Validated. Validated in Flow Cytometry and tested in Human. |
![]() Anti-Human CD28 Monoclonal Antibody PE Conjugated, Flow Validated |
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FC00065-PE | BosterBio | 25 tests, 100 tests | EUR 143 |
Description: Mouse Monoclonal Human CD28 Antibody PE Conjugated, Flow Validated. Validated in Flow Cytometry and tested in Human. |
![]() Anti-Human CD40 Monoclonal Antibody PE Conjugated, Flow Validated |
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FC00068-PE | BosterBio | 25 Tests, 100 Tests, 200 Tests | EUR 149 |
Description: Anti-Human CD40 Monoclonal Antibody PE Conjugated, Flow Validated |
![]() Anti-human CD14 Monoclonal Antibody PE Conjugated, Flow Validated |
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FC00137-PE | BosterBio | 25 Tests, 100 Tests, 200 Tests | EUR 153 |
Description: Mouse Monoclonal human CD14 Antibody PE Conjugated, Flow Validated. Validated in Flow Cytometry and tested in Human. |
![]() Anti-human CD11b Monoclonal Antibody PE Conjugated, Flow Validated |
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FC00144-PE | BosterBio | 25 Tests, 100 Tests, 200 Tests | EUR 153 |
Description: Mouse Monoclonal human CD11b Antibody PE Conjugated, Flow Validated. Validated in Flow Cytometry and tested in Human. |
![]() Anti-human CD19 Monoclonal Antibody PE Conjugated, Flow Validated |
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FC00154-PE | BosterBio | 25 Tests, 100 Tests, 200 Tests | EUR 108 |
Description: Mouse Monoclonal human CD19 Antibody PE Conjugated, Flow Validated. Validated in Flow Cytometry and tested in Human. |
![]() Anti-Human CD54 Monoclonal Antibody PE Conjugated, Flow Validated |
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FC00171-PE | BosterBio | 25 Tests, 100 Tests, 200 Tests | EUR 142 |
Description: Anti-Human CD54 Monoclonal Antibody PE Conjugated, Flow Validated |
![]() Anti-human CD38 Monoclonal Antibody PE Conjugated, Flow Validated |
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FC00193-PE | BosterBio | 25 Tests, 100 Tests, 200 Tests | EUR 153 |
Description: Mouse Monoclonal human CD38 Antibody PE Conjugated, Flow Validated. Validated in Flow Cytometry and tested in Human. |
![]() Anti-human CD25 Monoclonal Antibody PE Conjugated, Flow Validated |
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FC00214-PE | BosterBio | 25 Tests, 100 Tests, 200 Tests | EUR 125 |
Description: Mouse Monoclonal human CD25 Antibody PE Conjugated, Flow Validated. Validated in Flow Cytometry and tested in Human. |
![]() Anti-Human CD86 Monoclonal Antibody PE Conjugated, Flow Validated |
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FC00220-PE | BosterBio | 25 Tests, 100 Tests, 200 Tests | EUR 153 |
Description: Mouse Monoclonal Human CD86 Antibody PE Conjugated, Flow Validated. Validated in Flow Cytometry and tested in Human. |
![]() Anti-human CD4 Monoclonal Antibody PE Conjugated, Flow Validated |
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FC00344-PE | BosterBio | 25 Tests, 100 Tests, 200 Tests | EUR 113 |
Description: Mouse Monoclonal human CD4 Antibody PE Conjugated, Flow Validated. Validated in Flow Cytometry and tested in Human. |
![]() Anti-Human CD11c Monoclonal Antibody PE Conjugated, Flow Validated |
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FC00357-PE | BosterBio | 25 Tests | EUR 136 |
Description: Mouse Monoclonal Human CD11c Antibody PE Conjugated, Flow Validated. Validated in Flow Cytometry and tested in Human. |
![]() Anti-human CD5 Monoclonal Antibody PE Conjugated, Flow Validated |
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FC00480-PE | BosterBio | 25 Tests, 100 Tests, 200 Tests | EUR 153 |
Description: Mouse Monoclonal Anti-human CD5 PE Conjugated, designed for Flow Cytometry and validated by Flow Cytometry using Human cells. |
Comparative analysis between a medical system and regent dipsticks in measuring pH
En este estudio,comparamos las mediciones de pH cuando usamos un dispositivo médico portátil y diferentes tiras reactivas.
MATERIALES Y MÉTODOS: Se probaron cuatro marcas de tiras reactives de pH y un medidor de pH, Lit-Administration® pH Meter, utilizando soluciones tampón comerciales con siete valores de pH distintos que representan el rango fisiológico de pH en orina (4.66; 5.0; 5.5; 6.0;7.0; 7.5; 8.0). Se realizó un análisis estadístico para evaluar la correlación de los valores medidos versus los reales, junto con las medidas de validez como resolución,precisión y exactitud.
CONCLUSIÓN: El estudio comparativo detallado presentado aquí revela la superioridad de un medidor portátil de pH frente algunas de las marcas comerciales de tiras reactivas más ampliamente usadas en las práctica clínica. El Lit-Administration® pH Meter representa una alternativa fiable cuando se necesita un monitoreo del pH urinario, como puede suceder durante la detección de enfermedades o la monitorización del tratamiento a nivel clínico, así como durante el autocontrol domiciliario del paciente, bajo supervisión profesional.
![]() CD26 antibody (FITC) |
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61R-CD26aHUFT | Fitzgerald | 120 tests | EUR 413 |
Description: Mouse monoclonal CD26 antibody (FITC) |
![]() Dipeptidyl Peptidase 4 (CD26) Antibody (RPE) |
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abx412944-100tests | Abbexa | 100 tests | EUR 592 |
![]() Dipeptidyl Peptidase 4 (CD26) Antibody (RPE) |
|||
abx414068-100tests | Abbexa | 100 tests | EUR 592 |
![]() Dipeptidyl Peptidase 4 (CD26) Antibody (RPE) |
|||
abx414069-25tests | Abbexa | 25 tests | EUR 314 |
![]() Anti-Hu CD26 FITC |
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1F-608-T025 | ExBio | 25 tests | EUR 122 |
![]() Anti-Hu CD26 FITC |
|||
1F-608-T100 | ExBio | 100 tests | EUR 204 |
![]() anti- SR-BI antibody |
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FNab08215 | FN Test | 100µg | EUR 548.75 |
Description: Antibody raised against SR-BI |
![]() EZ-DNA Reagents |
|||
BS8202 | Bio Basic | 100preps | EUR 88.06 |
![]() EZ-DNA Reagents |
|||
SK8201 | Bio Basic | 100preps | EUR 93.5 |
![]() Mouse Anti Human Cd26 Monoclonal Antibody,RPE |
|||
CABT-45831MH | Creative Diagnostics | 100 TEST | EUR 710 |
![]() Rat Anti Mouse Cd26 Monoclonal Antibody,RPE |
|||
CABT-45844RM | Creative Diagnostics | 100 TEST | EUR 533 |
![]() Dipeptidyl Peptidase 4 (CD26) Antibody (PE) |
|||
abx200203-100tests | Abbexa | 100 tests | EUR 453 |
![]() Dipeptidyl Peptidase 4 (CD26) Antibody (PE) |
|||
abx139398-100tests | Abbexa | 100 tests | EUR 481 |
![]() BI 6727 |
|||
2222-1 | Biovision | EUR 120 |
![]() BI 6727 |
|||
2222-5 | Biovision | EUR 327 |
![]() BI-2536 |
|||
2370-25 | Biovision | EUR 523 |
![]() BI-2536 |
|||
2370-5 | Biovision | EUR 175 |
![]() BI-D1870 |
|||
1924-1 | Biovision | EUR 142 |
![]() BI-D1870 |
|||
1924-5 | Biovision | EUR 370 |
![]() BI-78D3 |
|||
B1686-25 | Biovision | EUR 528 |
![]() BI-78D3 |
|||
B1686-5 | Biovision | EUR 175 |
![]() BI-7273 |
|||
B1879-25 | Biovision | EUR 892 |
![]() BI-7273 |
|||
B1879-5 | Biovision | EUR 262 |
![]() BI-9564 |
|||
B1880-25 | Biovision | EUR 756 |
![]() BI-9564 |
|||
B1880-5 | Biovision | EUR 229 |
![]() BI-409306 |
|||
B2377-25 | Biovision | EUR 756 |
![]() BI-409306 |
|||
B2377-5 | Biovision | EUR 229 |
![]() BI-7273 |
|||
HY-100351 | MedChemExpress | 50mg | EUR 877 |
![]() BI-9564 |
|||
HY-100352 | MedChemExpress | 200mg | EUR 2254 |
![]() BI 689648 |
|||
HY-101217 | MedChemExpress | 25mg | EUR 2116 |
![]() BI-78D3 |
|||
HY-10366 | MedChemExpress | 25mg | EUR 349 |
![]() BI-6C9 |
|||
HY-103661 | MedChemExpress | 50mg | EUR 1083 |
![]() BI-D1870 |
|||
HY-10510 | MedChemExpress | 2mg | EUR 147 |
![]() BI-882370 |
|||
HY-107779 | MedChemExpress | 100mg | EUR 1164 |
![]() BI-3802 |
|||
HY-108705 | MedChemExpress | 10mg | EUR 911 |
![]() BI-3812 |
|||
HY-111381 | MedChemExpress | 25mg | EUR 1772 |
![]() BI-3663 |
|||
HY-111546 | MedChemExpress | 1mg | EUR 681 |
![]() BI-749327 |
|||
HY-111925 | MedChemExpress | 100mg | EUR 3092 |
![]() BI-409306 |
|||
HY-112831 | MedChemExpress | 50mg | EUR 2058 |
![]() BI-671800 |
|||
HY-114141 | MedChemExpress | 100mg | EUR 3092 |
![]() BI-1347 |
|||
HY-120350 | MedChemExpress | 10mM/1mL | EUR 176 |
![]() BI-167107 |
|||
HY-121251 | MedChemExpress | 100mg | EUR 2633 |
![]() BI-4464 |
|||
HY-124625 | MedChemExpress | 10mg | EUR 911 |
![]() BI 01383298 |
|||
HY-124738 | MedChemExpress | 10mM/1mL | EUR 163 |
![]() BI-4020 |
|||
HY-129550 | MedChemExpress | 10mg | EUR 681 |
![]() BI-9627 |
|||
HY-18071 | MedChemExpress | 5mg | EUR 291 |
![]() BI 224436 |
|||
HY-18595 | MedChemExpress | 5mg | EUR 533 |
![]() (±)-BI-D |
|||
HY-18601 | MedChemExpress | 100mg | EUR 2943 |
![]() BI-847325 |
|||
HY-18955 | MedChemExpress | 100mg | EUR 1262 |
![]() BI 2536 |
|||
HY-50698 | MedChemExpress | 100mg | EUR 1229 |
![]() BI-D1870 |
|||
B2227-10 | ApexBio | 10 mg | EUR 270 |
Description: BI-D1870 is a cell-permeable inhibitor of the p90 RSK isoforms with IC50 values of 31nM, 24nM, 18nM and 15nM for RSK1, RSK2, RSK3 and RSK4 respectively [1].BI-D1870 is a derivative of dihydropteridinone and found to be a remarkably specific inhibitor of RSK isoforms. |
![]() BI-D1870 |
|||
B2227-5 | ApexBio | 5 mg | EUR 189 |
Description: BI-D1870 is a cell-permeable inhibitor of the p90 RSK isoforms with IC50 values of 31nM, 24nM, 18nM and 15nM for RSK1, RSK2, RSK3 and RSK4 respectively [1].BI-D1870 is a derivative of dihydropteridinone and found to be a remarkably specific inhibitor of RSK isoforms. |
![]() BI-D1870 |
|||
B2227-5.1 | ApexBio | 10 mM (in 1mL DMSO) | EUR 235 |
Description: BI-D1870 is a cell-permeable inhibitor of the p90 RSK isoforms with IC50 values of 31nM, 24nM, 18nM and 15nM for RSK1, RSK2, RSK3 and RSK4 respectively [1].BI-D1870 is a derivative of dihydropteridinone and found to be a remarkably specific inhibitor of RSK isoforms. |
![]() BI-D1870 |
|||
B2227-50 | ApexBio | 50 mg | EUR 595 |
Description: BI-D1870 is a cell-permeable inhibitor of the p90 RSK isoforms with IC50 values of 31nM, 24nM, 18nM and 15nM for RSK1, RSK2, RSK3 and RSK4 respectively [1].BI-D1870 is a derivative of dihydropteridinone and found to be a remarkably specific inhibitor of RSK isoforms. |
![]() BI 6015 |
|||
B5668-10 | ApexBio | 10 mg | EUR 179 |
Description: BI 6015 is an antagonist of hepatocyte nuclear factor 4? [1]. Hepatocyte nuclear factor 4? (HNF4?) is a nuclear receptor and regulates gene expression in enterocytes, hepatocytes and pancreatic ? cells [1]. BI 6015 is a HNF4? antagonist. |
![]() BI 6015 |
|||
B5668-5 | ApexBio | 5 mg | EUR 118 |
Description: BI 6015 is an antagonist of hepatocyte nuclear factor 4? [1]. Hepatocyte nuclear factor 4? (HNF4?) is a nuclear receptor and regulates gene expression in enterocytes, hepatocytes and pancreatic ? cells [1]. BI 6015 is a HNF4? antagonist. |
![]() BI 6015 |
|||
B5668-50 | ApexBio | 50 mg | EUR 595 |
Description: BI 6015 is an antagonist of hepatocyte nuclear factor 4? [1]. Hepatocyte nuclear factor 4? (HNF4?) is a nuclear receptor and regulates gene expression in enterocytes, hepatocytes and pancreatic ? cells [1]. BI 6015 is a HNF4? antagonist. |
![]() BI-847325 |
|||
B6014-1 | ApexBio | 1 mg | EUR 132 |
Description: BI 847325 is a dual inhibitor of Ras-mitogen-activated protein kinase kinases (MEK) and Aurora kinases [1,2]. BI 847325 inhibits MEK1 and MEK2 with IC50 values of 25 and 4 nM, respectively. |
![]() BI-847325 |
|||
B6014-5 | ApexBio | 5 mg | EUR 242 |
Description: BI 847325 is a dual inhibitor of Ras-mitogen-activated protein kinase kinases (MEK) and Aurora kinases [1,2]. BI 847325 inhibits MEK1 and MEK2 with IC50 values of 25 and 4 nM, respectively. |
![]() BI-9564 |
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B6184-1 | ApexBio | 1 mg | EUR 109 |
Description: IC50: 75 nM and 3.4 ?M for BRD9 and BRD7 bromodomains, respectivelyBI-9564 is a BRD9/7 specific inhibitor.BRD7 and BRD9 are two important members of the bromodomain family protein. |
![]() BI-9564 |
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B6184-10 | ApexBio | 10 mg | EUR 293 |
Description: IC50: 75 nM and 3.4 ?M for BRD9 and BRD7 bromodomains, respectivelyBI-9564 is a BRD9/7 specific inhibitor.BRD7 and BRD9 are two important members of the bromodomain family protein. |
![]() BI-7273 |
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B6196-25 | ApexBio | 25 mg | EUR 437 |
Description: IC50: 19 and 117 nM for BRD9 and BRD7, respectively.BI-7273 is a BRD9 bromodomain inhibitor. |
![]() BI-7273 |
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B6196-5 | ApexBio | 5 mg | EUR 168 |
Description: IC50: 19 and 117 nM for BRD9 and BRD7, respectively.BI-7273 is a BRD9 bromodomain inhibitor. |
![]() BI 2536 |
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A3965-10 | ApexBio | 10 mg | EUR 224 |
Description: BI 2536 is a potent, ATP-competitive, well tolerated and highly specific human polo-like kinase 1 (PLK1) inhibitor with IC value of 0.83 nM, which shows 1000-fold selectivity against other kinases [1]. |
![]() BI 2536 |
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A3965-5 | ApexBio | 5 mg | EUR 148 |
Description: BI 2536 is a potent, ATP-competitive, well tolerated and highly specific human polo-like kinase 1 (PLK1) inhibitor with IC value of 0.83 nM, which shows 1000-fold selectivity against other kinases [1]. |
![]() BI 2536 |
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A3965-5.1 | ApexBio | 10 mM (in 1mL DMSO) | EUR 195 |
Description: BI 2536 is a potent, ATP-competitive, well tolerated and highly specific human polo-like kinase 1 (PLK1) inhibitor with IC value of 0.83 nM, which shows 1000-fold selectivity against other kinases [1]. |
![]() BI 2536 |
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A3965-50 | ApexBio | 50 mg | EUR 595 |
Description: BI 2536 is a potent, ATP-competitive, well tolerated and highly specific human polo-like kinase 1 (PLK1) inhibitor with IC value of 0.83 nM, which shows 1000-fold selectivity against other kinases [1]. |
![]() BI 2536 |
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A3965-S | ApexBio | Evaluation Sample | EUR 81 |
Description: BI 2536 is a potent, ATP-competitive, well tolerated and highly specific human polo-like kinase 1 (PLK1) inhibitor with IC value of 0.83 nM, which shows 1000-fold selectivity against other kinases [1]. |
![]() BI 78D3 |
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B9011-10 | ApexBio | 10 mg | EUR 216 |
Description: BI-78D3 is a substrate competitive inhibitor of JNK inhibitor [2].JNK is a member of the MAPK family. JNK is a stress-activated protein kinase that modulates pathways implicated in a variety of disease states. |
![]() BI 78D3 |
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B9011-100 | ApexBio | 100 mg | EUR 1094 |
Description: BI-78D3 is a substrate competitive inhibitor of JNK inhibitor [2].JNK is a member of the MAPK family. JNK is a stress-activated protein kinase that modulates pathways implicated in a variety of disease states. |
![]() BI 78D3 |
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B9011-25 | ApexBio | 25 mg | EUR 412 |
Description: BI-78D3 is a substrate competitive inhibitor of JNK inhibitor [2].JNK is a member of the MAPK family. JNK is a stress-activated protein kinase that modulates pathways implicated in a variety of disease states. |
![]() BI 78D3 |
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B9011-5 | ApexBio | 5 mg | EUR 161 |
Description: BI-78D3 is a substrate competitive inhibitor of JNK inhibitor [2].JNK is a member of the MAPK family. JNK is a stress-activated protein kinase that modulates pathways implicated in a variety of disease states. |
![]() BI 78D3 |
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B9011-5.1 | ApexBio | 10 mM (in 1mL DMSO) | EUR 183 |
Description: BI-78D3 is a substrate competitive inhibitor of JNK inhibitor [2].JNK is a member of the MAPK family. JNK is a stress-activated protein kinase that modulates pathways implicated in a variety of disease states. |
![]() BI 78D3 |
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B9011-50 | ApexBio | 50 mg | EUR 676 |
Description: BI-78D3 is a substrate competitive inhibitor of JNK inhibitor [2].JNK is a member of the MAPK family. JNK is a stress-activated protein kinase that modulates pathways implicated in a variety of disease states. |
![]() Goat Anti-Camel IgG-RPE conjugate |
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30835-RPE | Alpha Diagnostics | 0.5 ml | EUR 263 |
![]() Mouse IgG-PE conjugate (isotype control) |
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20008-PE | Alpha Diagnostics | 50 Tests | EUR 164 |
![]() Rabbit IgG-PE conjugate (isotype control) |
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20009-PE | Alpha Diagnostics | 100 tests | EUR 225 |
![]() Goat IgG-PE conjugate (isotype control) |
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20011-PE | Alpha Diagnostics | 100 tests | EUR 225 |
![]() Monoclonal Anti-Rat IgG1-PE Conjugate |
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50126-PE | Alpha Diagnostics | 0.1 ml | EUR 347 |
![]() CD26 |
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26A-100T | ImmunoStep | 100 test | EUR 349 |
![]() CD26 |
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26B-01MG | ImmunoStep | 100 test | EUR 284 |
![]() CD26 |
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26CFB-100T | ImmunoStep | 100 test | EUR 388 |
![]() CD26 |
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26F-100T | ImmunoStep | 100 test | EUR 297 |
![]() CD26 |
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26PE-100T | ImmunoStep | 100 test | EUR 362 |
![]() CD26 |
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26PP-100T | ImmunoStep | 100 test | EUR 415.3 |
![]() CD26 |
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26PU-01MG | ImmunoStep | 0,1 mg | EUR 219 |
![]() Dipeptidyl Peptidase 4 (CD26) Antibody (FITC) |
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abx412942-01mg | Abbexa | 0.1 mg | EUR 509 |
![]() Dipeptidyl Peptidase 4 (CD26) Antibody (FITC) |
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abx414066-01mg | Abbexa | 0.1 mg | EUR 509 |
![]() Dipeptidyl Peptidase 4 (CD26) Antibody (FITC) |
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abx200202-100tests | Abbexa | 100 tests | EUR 398 |
![]() Dipeptidyl Peptidase 4 (CD26) Antibody (FITC) |
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abx139400-100tests | Abbexa | 100 tests | EUR 425 |
![]() Set of 10 Biolipidure Reagents |
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Biolipidure-set | Biolipidure | 10mLx10 | EUR 1517 |
Description: Set of 10 Biolipidure Reagents, whose applications include Immunoassays, Western blots, Immunohistochemistry, Turbidimetric assays, Immunochromatography, and Bead based assays. Benefits include: No lot to lot variation, No animal derived materials, Non-specific adsorption suppression, Stabilization of immobilized antibody, Stabilization of enzyme-antibody conjugate, Enzyme-substrate reaction enhancement and aggregation reaction enhancement |
![]() Rat IgG-PE conjugate (isotype control) (Isotype control) |
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20005-PE | Alpha Diagnostics | 25 tests | EUR 202 |
![]() Dipeptidyl Peptidase 4 / CD26 (DPP4) Antibody (FITC) |
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20-abx335362 | Abbexa |
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