Month: August 2020

August 26, 2020

Cross-Couplings between Alkyl Halides and Grignard Reagents

Cobalt-Catalyzed Cross-Couplings between Alkyl Halides and Grignard Reagents ConspectusMetal-catalyzed cross-couplings have emerged as necessary devices for the event of C-C bonds. The identification of setting pleasant catalytic packages along with huge substrate scope made these cross-couplings key reactions to entry useful molecules ranging from provides, agrochemicals to vigorous pharmaceutical parts. They have been an increasing number of built-in in retrosynthetic plans, allowing shorter and genuine […]

August 26, 2020

Commercially available transaction reagents 

Commercially out there transaction reagents and damaging management siRNA will not be inert The transfection of artificial small interfering (si)RNA into cultured cells kinds the premise of research that use RNA interference (generally known as “gene knockdown”) to check the impression of lack of gene or protein expression on a organic pathway or course of. In these research, mock transfections (with transfection reagents alone), and the […]

August 26, 2020

Formation of N-nitrosodimethylamine During the storage of Ranitidine reagent powders and tablets

Temperature-dependent formation of N-nitrosodimethylamine during the storage of ranitidine reagent powders and tablets The purpose of this study was to elucidate the effect of high-temperature storage on the stability of ranitidine, specifically with respect to the potential formation of N-nitrosodimethylamine (NDMA), which is classified as a probable human carcinogen. Commercially available ranitidine reagent powders and formulations were stored under various conditions, and subjected to LC-MS/MS analysis. When […]

August 26, 2020

Western Blotting by Direct Deposition of Reagents onto Capture Membrane

Fast Immunoassay for Microfluidic Western Blotting by Direct Deposition of Reagents onto Capture Membrane Western blotting is a widely used protein assay platform, but the technique requires long analysis times and multiple manual steps. Microfluidic systems are currently being explored for increased automation and reduction of analysis times, sample volumes, and reagent consumption for western blots. Previous work has demonstrated that proteins separated by microchip electrophoresis can […]

August 26, 2020

Bioreagents for protein chips

Generation of bioreagents for protein chips. Protein microarrays have the potential to dramatically increase the throughput of proteomic analysis. Protein expression profiling chips with distinct spots of immobilized protein capture agents will allow the simultaneous measurement of hundreds to thousands of proteins from one sample. In contrast to DNA chips, for which the capture probes are easily designed and synthesized, the development of content for protein biochips […]